Cryogenic freezing
Cryogenic freezing is a very important method in biotechnology and preservation. It stops biological and chemical activity by making things very cold. This method, which began to develop in the early 1900s, is now very important in medicine for keeping organs, embryos, and stem cells alive. It has made new treatments and research possible. In biology, it's especially important to keep samples of bacteria and plants, which helps with research and conservation. In the food business, it keeps food fresh and safe for a longer time. Cryogenic freezers and liquid nitrogen are used to keep the temperature just right. This is very important for many fields, such as biomedicine, cell culture, and food preservation. Cryogenic freezing is a combination of science and engineering that has an impact on many areas, such as healthcare and food storage.
Principle of operation
The main idea behind cryogenic freezing is to keep biological material safe by using extremely low temperatures (cryogenic temperatures) in a controlled way. This could be anything from individual cells to whole tissues and food items. This cryonics process is carefully thought out so that the material will still be usable and whole when it thaws.
The first step in cooling is to quickly bring the material down to cryogenic temperatures, which is usually done with liquid nitrogen. This prevents ice crystal formation, which can hurt cell structures. It's very important for biological material to stay stable for a long time that it goes from very hot to very cold very quickly.
After being cooled down, the storage phase keeps the material at these very low temperatures, which keeps it safe from further damage. It is very important to keep the temperature stable during this phase so that it doesn't change. If it does, the material could partially thaw and be damaged.
The last step, thawing, is a carefully controlled cooling process that keeps the material from getting too hot and causes the least amount of damage.
What equipment is used
To keep the temperature just right and the biological material safe, a cryogenic freezer needs a lot of different tools. Cryogenic chambers and vessels are the main parts of this process. They keep the very low temperatures needed for cryo preservation. Cryogenic technology often uses liquid nitrogen because it can quickly cool things down to -196°C, which stops biological activity and keeps the item in a state of suspended animation.
It's just as important to have systems for cooling and controlling temperature. They have very advanced sensors and algorithms that can keep an eye on and change temperatures very accurately. This makes sure that the biological samples cool down at a steady and controlled rate. This is very important because crystal formation can damage cell structures.
Some biological things, like cells, tissues, and organs, need more advanced equipment to be cryopreserved. This includes cryogenic freezers, which can cool and store different types of biological materials in different ways. The kind of equipment you need depends on how big it is, how easily it can be damaged by ice, and what you plan to do with it after it thaws.
Which Mirai products can be used in cryogenic freezing
Any Mirai Intex equipment can work with advanced cryogenic chambers, freezers, and temperature control systems that are designed to be very safe and effective in cryopreservation applications.
These machines use the most advanced and environmentally friendly ways to cool things down. This makes it easier to control the temperature and adds safety features to keep cryopreserved materials safe in medicine, biotechnology, and food science.
Also, the importance of environmentally friendly cooling is a key factor for Mirai in the production of its machines, especially for applications related to human health and life in general.
Mirai has a huge experience in applications for biobanking, storage and freeze-drying of biosamples and food. Projects realized with market leaders in these industries, which emphasizes the reliability of Mirai machines.
But application in cell culture, organ transplantation, stem cell research would highlight Mirai's commitment to supporting the critical needs of scientific research and healthcare.
Development prospects
Cryogenic freezing has a bright future because new methods are being developed to make it easier to protect biological materials. These new things could be very useful for medicine and biotechnology. For example, they could make organ transplants and stem cell research more likely to work. Cryogenic technologies are also used in other areas, such as food science, where they help keep food fresh, and engineering, where they change the properties of materials to make them easier to work with.
